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Rhodococcus equi in Horses: Distribution and Virulence Factors


Kelly A. Cunningham

Department of Dairy and Animal Science
Penn State

 

Rhodococcus equi is a soil-dwelling bacterium found on almost every mid- to large-scale breeding farm in the world. Infection occurs in foals after inhalation of bacteria and manifests as coughing, wheezing, and lung abscesses. A high mortality rate makes this infectious organism a concern, as it has a tendency to spread even under acknowledged disease management practices. This summer’s work at Penn State investigated the current distribution of R. equi in a model Quarter horse breeding herd. A new R. equi-selective medium, developed by Dr. Gary Muscatello of the University of Melbourne, was used to culture samples. Positive results were obtained from a number of foals, and most were identified as one of several species of Corynebacterium. R. equi reference strains did not come up positive, however, raising questions about the validity of tests used.  Future investigation on the samples collected from this farm will include a simple set of tests suggested by Dr. Muscatello, while the study’s long-term goal is to speciate any strains of R. equi present at the Penn State facility.
 

This study was supported by an undergraduate student research grant from the College of Agricultural Sciences at Penn State.